PROCEDURE FOR DETERMINATION OF THE FILLED VOLUME OF AMPOULES AND VIALS.

PROCEDURE FOR DETERMINATION OF THE FILLED VOLUME OF AMPOULES AND VIALS.

Procedure

Precautions:

• Use protective hand gloves.
• Ensure that the limit of fill weight of the ampoule / vial is given  in the respective BMR

           Operation:

• Keep the weighing balance on the vibration free table.
• Switch on the weighing balance. Ensure that the pan of weighing balance is completely cleaned.
• Ensure weighing balance is showing ‘zero’ reading.
• Ensure that the weighing balance is calibrated.
• Keep the filled unsealed ampoule on the pan of weighing balance.
• Note down the position of the filled ampoule on the filling Machine.
• Remove all solution from the ampoule.
• Ensure that the solution is completely removed out.
• Again weigh the empty ampoule after removing solution.
• The weight of the solution would be the difference between the weight of the filled unsealed ampoule and empty ampoules.
• The weight of the solution should be within the range.
• Discard the ampoule after checking the volume.