January 2019 ~ Natural herbs

Wednesday, January 30, 2019

PRINT AND APPLY LABEL MACHINES

Print & apply labelers are ideal for high-resolution text, bar codes and images on cases, pallets and shrink wrap, delivering high contrast print for exceptional bar code reading rates. Videojet print & apply labelers utilize Direct Apply™ technology, a unique on-demand labeling method that allows accurate placement of the label onto the package without the need for an applicator – even at high speeds.


Automated label application machine and label application machine or labeling machine
Scinomix has experience in labeling tubes, microplates, deepwell blocks, and many different types of vials including Matrix, Micronic, Cryovials.
Tube Labelers
Automated label application machine 


Saturday, January 26, 2019


The marketing mix definition is simple. It is about putting the right product or a combination thereof in the place, at the right time, and at the right price. The difficult part is doing this well, as you need to know every aspect of your business plan.


VIAL FILLING AND CAPPING MACHINE

 Sterile Dosage form are the preparations free from pyrogens and micro-organism they are injected in the body. All the sterile dosage form are pyrogen free, bacteria free and perculate matter free. There should be no visible particle in the preparations.

SVP and LVP liquid and powders are formed and they are sterile products.

Before we go into every one of the components of the promoting blend, and to stay away from disarray between the 4p's, 7p's and even the 4c's – you should focus at the picture underneath to comprehend what makes up the whole advertising blend. The picture above is an oversimplified graph of the components that are incorporated into a showcasing blend. 

Sun Pharmaceutical Industries Limited is a pharmaceuticals organization. The Company's business portions incorporate US Business, Indian Branded Generics Business, Emerging Markets, Global Consumer Healthcare Business and Active Pharmaceutical Ingredients (API).


 How can I invest in share market? 


So as to have the capacity to put resources into offer market in India, the accompanying strategies should be pursued.

Get a PAN or Aadhar card
Container card or an Aadhar card is a compulsory prerequisite for putting resources into India. It is required for KYC (know your customer) methodology while opening a record with the market controller, the Securities and Exchange Board of India (Sebi). Other than this, the administration has commanded half year bank proclamation alongside a dropped check, under the new guidelines to open a demat account.

Friday, January 25, 2019

Cipla pharma share price 

Cipla LTD

Cipla is a pharmaceuticals headquartered is situated in Mumbai. It has presence in over 80 countries, with its 43 manufacturing facilities and a portfolio including more than 1,500 products across a wide range of therapeutic categories. It has a workforce of more than 23,000, according to its annual report 2017. In FY17, Cipla registered a net profit of Rs 975 crore over revenue of Rs 10,975 crore. 

Sunpharma share price
It is a private sector pharmaceuticals company. Sun Pharmaceuticals Industries is among the top 10 consumer healthcare companies in India, Romania, Nigeria and Myanmar
Sun Pharmaceuticals Industries manufactures and markets a large basket of pharmaceutical formulations covering a broad spectrum of chronic and acute therapies. Headquartered in Mumbai,


Wednesday, January 23, 2019


STANDARD OPERATING PROCEDURE FOR FILTRATION OF THE RELEASED BULK SOLUTION.
          Requirements:          
v  Entire Pre-sterilized Unit, which includes Pressure vessel, filling
v  vessels,  pre-sterilized membrane holder fitted with appropriate fiber
v  glass  filter of  1.5 micron followed by membrane of appropriate porosity as  per product.


  Procedure for performing Bubble point test.

o   Requirements:
§  Bubble point test assembly.
o   Procedures:
§  Remove the sterilized membrane filter assembly in sterile area.
§  Attach sterile silicon tubing at both ends.

FILTRATION OF BULK SOLUTION

Process Of Filtration ! Filtration is the process of separating suspended solid matter from a liquid, by causing the latter to pass through the pores of a membrane, called a filter.
While preparing tea, a filter or a sieve is used to separate tea leaves from the water.
Filter sieve is called as filtering media, the tea leaves collected on filter mesh is called as filter cake and the solution passes from filter media and collected on collecting vessel is known as filtrate.

BULK SOLUTION- The solution present in bulk quantity for the filtration process.

FILTER MEDIA- It is the medium which is used for the filtration from which solution is passed or solid undissolved particles are retained on it.
It may be Paper,membrane, sintered glass Filter media or sintered filter candle.
The   

v Filtration of the bulk solution is done by transferring the solution to the pressure vessel of any size like 50-100 L.

v Close the pressure vessel and attach the silicon pipe to it.

v Open the tap of the filter assembly having the two openings as shown in fig.

v To top end attach the pipe which is further attached to top of pressure vessel

v And attach the bottom end of filtering assembly to the top of another collecting vessel or pressure vessel.

v Attach another silicon tube to 1st pressure vessel having solution to be filtered.

v Now Apply nitrogen gas which provide pressure in vessel and solution from the vessel comes out from vessel to filter assembly and filtration takes place

v Filtrate is collecting to collecting vessel.

v Solid or undissolved particles are retained on filter membrane or filter paper .





Tuesday, January 22, 2019


Precautions And Instructions:
Ø  Ensure that the chamber of the autoclave is cleaned properly.
Ø  Ensure that the main steam line pressure is sufficient to operate the autoclave (i.e. minimum required steam pressure = 6.0 Kg/cm2 )


 RUBBER STOPPER MACHINE. 
Procedure
o   Wear the hand gloves.
o   Take sufficient quantity of rubber stoppers in clean plastic tub.
o   Soak in 1% Teepol solution and give frequent wash with purified water by vigorous agitation, till Teepol solution will be removed completely.

Thursday, January 10, 2019


GRANULATION PROCESS:



Granulation process :- 
It is a process in which the powder particles are made to adhere to form larger, multi particle entities called granules. A dough mass is prepared to form the granules.

Acne is inflammation of the skin, due to blockage of skin pores. Blockage occurs due to an excessive secretion from the sebaceous glands and accumulated, dead skin cells. This combination encourages the skin bacterium Propioni bacterium which multiplies and causes increased skin inflammation. Acne comes from the Greek word, acme, meaning skin eruption.


STERILE FILLING AND SEALING PROCESS


 Sterile Dosage form are the preparations free from pyrogens and micro-organism they are injected in the body. All the sterile dosage form are pyrogen free, bacteria free and perculate matter free. There should be no visible particle in the preparations.

SVP and LVP liquid and powders are formed and they are sterile products.

"If we informed women about the possibility of performing BSE at repeat cesarean section for ovarian cancer prevention, it is likely that many women would opt for this procedure,“ writes Dr. Westgren. He suggests that gynecology professionals discuss changing policies and setting up randomized trials to further understand how BSE could reduce ovarian cancer risk. 

My choice is basically between becoming a doctor and become a pharmacist.Unless there are

other secure,well paying jobs you know of .I really had to search deeply to answer this question for myself.

FLOW DIAGRAM OF PURIFIED WATER GENERATION PLANT


A. PERFUMES :

it is any substance which is made from natural or synthetic materials, or a combination of both, employed for creating a pleasant odor. Such type of materials are combined by a perfumer for producing the pleasing fragrance. The use of perfumes goes back into the history when people used to burn fragrant resins, woods and gums as incenses. The term perfume has been derived from Latin words per, meaning through, and fumes meaning smoke. Perfume making was one of the important arts in old days.


v   Abbreviations and Definitions:
·         SOP   :          Standard Operating Procedure; a document where step by step instructions are cited to serve as support for methods or manners of fulfilling a function or functions reliably and consistently. 

ENTRY AND EXIT PROCEDURE:

Entry procedure for Gents
v  Remove the street footwear and keep in the rack provided for the same in passage in front of change room.
v  Open the door and enter in to the change room.

 DETERMINATION OF THE FILLED VOLUME OF VIALS:

v  Procedure
§  Precautions:
§  Use protective hand gloves.
§  Ensure that the limit of fill weight/volume of the vial is given in the respective BMR.

PRECAUTIONS DURING PRODUCTION ACTIVITY
v  Dispensing of all the raw materials should be done in dispensing area, which should be maintained 
v  Clean, dust free and hygienic to prevent contamination. Dispensed raw material should be labeled and 


Cleaning and Disinfection of the Sterile Area after Simulation trial run studies.

v  Precautions:
§  Wiping of all surfaces should be done with a lint free mop.
§  Mops used for wiping of area and equipment where there is media spillage should be permanently discarded after cleaning and wiping.
§  All tubing used for Simulation trial run studies shall be destroyed and it should not be used for other products.


PROCEDURE FOR OPERATION OF VIALS LABELING MACHINE.
Procedure
·         Switch on the vials labeling machine.
·         Carry out the line clearance of the vials labeling machine and area.
·         Bring the containers of the batch to be labeled near the vials labeling machine.
·         Feed some vials in feeding hopper.

Wednesday, January 9, 2019

PROCEDURE FOR DETERMINATION OF THE FILLED VOLUME OF AMPOULES AND VIALS.
Procedure
Precautions:
  • Use protective hand gloves.
  • Ensure that the limit of fill weight of the ampoule / vial is given  in the respective BMR

To clean and disinfect the foot wears used in sterile area.

1.    At the end of working day collect all the used foot wears in big plastic bags.
Disinfectant



SOP- Fumigation

Objective : To lay down a procedure for fumigation using fogger.
Scope : This procedure is applicable to the production & QC.
Responsibility :
1.                  Operator, Production is responsible to follow this SOP.
2.     Production Chemist/Officer / Head of the Department shall be responsible for the implementation of this SOP.
3.                  QA Officer shall be responsible for compliance of the SOP.

PROCEDURE FOR CLEANING OF LAMINAR AIR FLOW


Procedure:
        Preacautions:
Use protective hand gloves.
                              Switch ‘OFF’ the laminar air flow if it is ‘ON’.
After switching ‘OFF’ the LAF ensure that the manometer is showing ‘zero’ reading.

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PERFUMES AND FLAVOURS

A. PERFUMES : it is any substance which is made from natural or synthetic materials, or a combination of both, employed for creating a ...

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